2 billion to 600 million years ago 🌋☄️, an ancient bacterium entered a pre-eukaryote and changed world affairs like almost no other event 📈. Whether that entering was a voluntary step, or if that bacterium was simply gulped down, we can’t tell for sure.
What we know for sure is that a paradigm shift happened, and instead of being digested (or the pre-eukaryote being “infected” for that matter) that bacterium made itself at home in that cell. Both, the pre-eukaryote and the ancient bacterium lived happily ever after 🫂🤗.
You guessed it, or knew it from the beginning: that ancient bacterium was the ancestor of today’s mitochondria.
So, to cut the 2 billion year story short: Do not use antibiotics in your cell culture medium, if you can avoid it. For continuous cell lines, they can be avoided.
💡 The antibiotics might have an effect on the mitochondria of your cells.
💡 It is much more likely that your way to work will get irreversibly sloppy in the cell culture lab.
💡 Antibiotics resistance do not simply come out of nowhere. Responsible handling of antibiotics should be taught at school!
If you use antibiotics for continuous cell lines, what is your excuse? 🫵👀
#Antibiotics #GCCP #CellCulture #LabSkills #LabLife #AntibioticsResistance
Author: asban